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Phycocyanin

The blue pigment that makes spirulina what it is.

C-phycocyanine (extraite d'Arthrospira platensis)Biliprotéine — tétrapyrrole à magnésium92 UB
Tradition

The ancestral story

Spirulina has been eaten continuously by two human civilisations, each of them documented.

The Aztecs harvested what they called tecuitlatl from the surface of Lake Texcoco, in the Valley of Mexico, before the Spanish conquest. Bernardino de Sahagún describes it in his Historia general de las cosas de Nueva España (1521): the inhabitants dried it into blue-green cakes and made broths with it. The city of Tenochtitlan had an organised production.

The Kanembu, a people of the shores of Lake Chad in Africa, have eaten dihé — wild spirulina harvested by hand, sun-dried and made into a protein-rich condiment — for at least several centuries. Without interruption, to this day.

These two peoples had no contact. They independently discovered the same organism, for the same use. That is a strong signal.

Science

What it is

Phycocyanin is a protein-pigment that gives spirulina its deep blue-turquoise colour. It belongs to the family of biliproteins — molecules whose tetrapyrrole structure resembles that of human haemoglobin, but whose central atom is magnesium instead of iron.

In other words: phycocyanin is to the cyanobacterium what haemoglobin is to human blood. A carrier of light rather than of oxygen. A primordial molecule, 3.5 billion years old, which learned to capture solar radiation to nourish the first life on Earth.

Isolated from fresh or low-temperature-dried spirulina, it makes up between 10 and 15% of the alga's dry weight. This concentration explains why it is extracted separately: to obtain an active dose, one would have to swallow several grams of whole spirulina.

What it unfolds in the body

Targeted anti-inflammatory

Phycocyanin selectively inhibits the COX-2 enzyme — the same mechanism as many pharmaceutical anti-inflammatories, but with no effect on COX-1 (the one that protects the stomach lining). No digestive side effects, unlike NSAIDs.

A powerful antioxidant

In several in vitro studies, its capacity to neutralise oxygen free radicals exceeds that of vitamin C, weight for weight. It acts especially on peroxyl and hydroxyl radicals — the most destructive for cell membranes.

Hepatoprotective

Several studies show protection of the liver against hepatotropic toxins (carbon tetrachloride, high-dose paracetamol). Phycocyanin appears to support liver-cell function without overstimulation.

Stimulates erythropoiesis

It increases the production of haematopoietic stem cells in the bone marrow — hence its historical place in convalescence protocols.

The Subtle

Subtle signature

Vibrational level92 UB

Bovis scale — indicative, never dogmatic.

« J'ai commencé à travailler la phycocyanine en 2018. Au début, c'était pour sa couleur — ce bleu n'existe pas ailleurs dans la nature alimentaire. Puis j'ai compris qu'elle travaille à un autre niveau : la régénération silencieuse pendant que les autres ingrédients portent le goût et l'énergie immédiate. Je la dose autour de 150-200 mg par formule, toujours crue, toujours associée à une graisse noble pour stabiliser le pigment. »

— Virgile, Corbières, Mars 2026

How I use it

Phycocyanin is at the heart of my Regenerative formula (ILA bar, Maison ilā retreat) and of the everyday Vanilla & Blue Spirulina bar. Paired with acacia honey (the register of ether / dawn / light), vanilla and a white-cacao base, it composes what I call the blue bar — the one we take on waking from a retreat, or after a long effort that has drawn deep on the system.

It pairs poorly with strong fermentations (miso, soy sauce) and dense bitter tastes (coffee, heavily roasted cacao). It needs a neutral or gentle context to express its identity.

In the kitchen

Where I find it — my gems

Pure food-grade phycocyanin is rare. Most blue powders on the market are blends (E133, maltodextrin, low concentration). I source from French artisanal producers who cultivate spirulina in low-temperature freshwater basins, extract the phycocyanin by cold membrane filtration (never above 40°C), and dry it without solvent.

See my gem suppliers →

Frequently asked

What is the difference between spirulina and phycocyanin?▾

Spirulina is the whole alga (proteins, minerals, carotenoids, chlorophyll, and 10–15% phycocyanin). Phycocyanin is the blue molecule extracted from it. One is a food; the other, a concentrated active principle.

In what amount?▾

Clinical studies use between 1 and 2 grams of pure phycocyanin per day for marked anti-inflammatory effects. For everyday maintenance, 200 to 500 mg is enough.

Is it compatible with anticoagulant medication?▾

Phycocyanin has a slight blood-thinning effect. Best avoided alongside anticoagulant medication without medical advice.

Why is it so costly?▾

Because one gram of pure phycocyanin takes 8 to 10 grams of fresh spirulina, followed by a cold membrane extraction that preserves the molecule. The process is slow, artisanal, and excludes any solvent.

Sources

Each source is ranked within a three-level ethical framework: documented tradition, recognised independent researcher, verified peer-reviewed study with no declared conflict of interest.

  1. Level 1

    Bernardino de Sahagún. Historia general de las cosas de Nueva España, 1521

    Documente la récolte de tecuitlatl (spiruline séchée) par les Aztèques au lac Texcoco.

  2. Level 1

    Consommation de la dihé par les Kanembou (lac Tchad)

    Pratique traditionnelle documentée par l'ethnobotanique, consommation continue de spiruline sauvage séchée depuis plusieurs siècles.

  3. Level 2

    Ripley D. Fox. Spiruline — technique, pratique et promesse, Édisud

    Fondateur d'Antenna France, pionnier de la spiruline en Afrique. Chercheur indépendant sans conflit d'intérêts.

  4. Level 2

    Clément Zarrouk. Conditions de croissance d'Arthrospira platensis, Université d'Alger, 1966

    Base académique de référence, utilisée sans lien industriel depuis 60 ans.

  5. Level 3

    Études cubaines (Romay et al.) sur l'anti-inflammatoire de la C-phycocyanine

    À vérifier manuellement (DOI et section Conflict of interest) avant publication — institution publique, pas de lien pharma identifié à ce stade.

    ⚠ À vérifier manuellement avant publication publique.

  6. Level 3

    Recherches indiennes CSIR sur l'hépatoprotection

    Council of Scientific and Industrial Research — institution publique indienne. À vérifier manuellement avant publication.

    ⚠ À vérifier manuellement avant publication publique.

See also

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